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On the other hand, Jewell and her group reported in 2015 that mTORC1 activation could be independent of the Rag GTPases and supported the fact that mTORC1 is differentially regulated by the amino acids leucine and glutamine

This inositol paradox causes a marked reduction in the MI/DCI ratio in ovarian follicular fluid compared to healthy controls (0.2:1 in PCOS patients vs

Oxidative damage to biomolecules might not initiate aging and disease processes, but rather might be a secondary effect of other initiating events

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Similarly, oxidative stress can lead to food deterioration through lipid oxidation and the accumulation of secondary peroxidation products in the food industry [87]