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10.1007/bf00691853 167 KitagawaK.MatsumotoM.KuwabaraK.TagayaM.OhtsukiT.HataR.et al

Treatments for Dysautonomia Beneficial lifestyle approaches Increased fluid and salt intake to optimize circulation and improve blood flow Compression stockings Abdominal binder to help pump blood back up to the heart and brain Patient-tailored exercise programs designed for patients with dysautonomia since exercise may not be well-tolerated Medications Medications to improve gut motility Medications to improve circulation By reducing heart rate By increasing blood pressure Medications to target autonomic nervous system In clinical trials, immunomodulating medications such as IVIg (Intravenous Immunoglobulin) are being studied Antimicrobials for ongoing infections Different infection-associated dysautonomia and POTS syndromes present with similar symptoms and may share common underlying pathologic mechanisms

The mechanism may be related to the decreased inflow of iron, TF and TFR1, the upregulation of GPX4, xCT, and FTH1, and the downregulation of ACSL4, MDA and LPO levels

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Nat Commun (2015) 6:6221