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In this review, we discuss the various molecular mechanisms interlinking the circadian rhythm with the Nrf2 pathway and contributing to breast cancer pathogenesis, we also talk about how these two pathways work in close association with the cell cycle which is another oscillatory system, and whether this interplay can be exploited to overcome drug resistance during chemotherapy

[DOI] [PubMed] [Google Scholar] 44.Collado M, Serrano M

mTOR signaling in human diseases Aberrant mTOR signaling is commonly associated with a wide range of diseases, including cancer, diabetes, obesity, various neurological disorders and other pathologies

The history of KPV is closely tied to the study of the alpha-melanocyte-stimulating hormone (-MSH), a peptide hormone known for its role in pigmentation, inflammation, and immune modulation

Its ability to stimulate collagen synthesis, glycosaminoglycan production, and balanced tissue remodeling is supported by multiple studies