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Translating these research results into clinical practice still requires overcoming multiple challenges, such as individualized treatment, long-term safety and patient compliance, which is a long process

Yao constructed a mutant recombinant luciferase reporter gene (pGL3.0-GPX4-M1) based on pGL3.0-GPX4-P1, discovering that mutations in pGL3.0-GPX4-P1 block IRF1-mediated fluorescence decay

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10.1159/000329956 24 BissingerR.WaibelS.BouguerraG.Al Mamun BhuyanA.AbbsS.LangF

GPS has the ability to control the expression of genes that are involved in lipid metabolism, including peroxisome proliferator-activated receptor- (PPAR-) and sterol regulatory element-binding protein-1c (SREBP-1c)