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Shalet et al., 1979

Extensive scholarly research has shown that nitric oxide, hydrogen peroxide, hydroxyl radicals, and superoxide anion are essential components of oxidative stress, which ultimately results in Alzheimers disease (593)

PLGA and other biodegradable carriers can readily be functionalized with GSH-cleavable linkers or redox-sensing moieties, providing clinically tractable routes to translate GSH-responsive designs into precision treatments [23]

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