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In pathologic conditions, the loss of HS disrupts the charge selectivity of the glomerular filtration barrier, which increases the filtration of proteins and leads to proteinuria (97)

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[131] [132] Species from the following genera and the following individual species are known to synthesize B 12 : Propionibacterium shermanii , Pseudomonas denitrificans , Streptomyces griseus , Acetobacterium , Aerobacter , Agrobacterium , Alcaligenes , Azotobacter , Bacillus , Clostridium , Corynebacterium , Flavobacterium , Lactobacillus , Micromonospora , Mycobacterium , Nocardia , Proteus , Rhizobium , Salmonella , Serratia , Streptococcus and Xanthomonas