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Caillot, M

For example, when a respiratory viral infection is combined with invasive fungal disease, cytokines attract more immune cells, which in turn produce more cytokines, creating an inflammatory cycle that damages lung tissues and causes the formation of fibrin and scar tissue, which allows fluids to seep into and fill the lung cavities, leading to respiratory failure (66)

Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation

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Summary The reason is because your tiny blood vessels can be pierced during injection