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8 Clinical application prospects of DPP1 inhibitors 8.1 Bronchiectasis Bronchiectasis represents a chronic respiratory disease characterized by permanent and abnormal bronchial dilation, usually secondary to recurrent airway infections and inflammation ( Current clinical practice lacks specific therapies approved for treating bronchiectasis, with clinical management primarily relying on empirical treatment strategies including antibiotic use, airway secretion clearance techniques, and bronchodilator application

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Thus, miR-126 can provide a crucial bridge between metabolic disturbances and neurotoxicity through the association with BDNF and their common signaling cascades in the pathogenesis of neurodegenerative disease, including PD and AD [33]

Cytokine Growth Factor Rev 13: 4159 [DOI] [PubMed] [Google Scholar] Miller C.T., Lin L., Casper A.M., Lim J., Thomas D.G., Orringer M.B., et al