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Abstract Type 2 diabetes mellitus (T2DM) is significantly associated with oxidative stress, resulting from the imbalance between reactive oxygen species (ROS) production and antioxidant defenses

Indeed, the expression of a c-GPx4 transgene in GPx4 -/- mice rescued the homozygous knockout phenotype by restoring embryonic viability whereas transgenic m-GPx4 expression failed to restore embryonic viability

However, there are insufficient studies on curcumin cooperating with the sestrin family to inhibit tumors, and the mechanism is still unclear

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The A 670 / A 520 ratio of the system did not decrease any more after 60 min, which indicated that the enzyme reaction was nearly completed within 1 h under the condition