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Sulfa and sulfite allergies are distinct and refer to allergic reactions to two different types of compounds

TJ complexes are primarily composed of transmembrane proteins including occludins, junctional adhesion molecules, and claudin family members that function collectively to form pores with selective permeability to ions and molecules (Brenchley and Douek 2012

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Thus, in the future, breakdown of the vicious cycle through modulating mitochondrial function is a potential therapeutic strategy in the management of sepsis (Fig