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The Metabolic Profile of Autism Autism is a complex neurodevelopmental disorder whose cause is unknown and which is diagnosed solely on behavioral criteria [63]

GSH (Glutathione) is an essential substrate for GPX4, which utilizes GSH as a reducing agent to convert toxic lipid peroxides into non-toxic lipid alcohols, thereby suppressing lipid peroxidation and the occurrence of ferroptosis 11

Briefly, RAW 264.7 cells were washed three times with phosphate buffer saline (PBS, Corning) and then incubated in ice-cold hypotonic lysing buffer (50 mM TrisHCl, 10 mM magnesium sulfate at pH 7.5) for 4 h at 4 C

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