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By preserving muscle mass during weight loss, patients set themselves up for easier weight maintenance, better physical function, and improved metabolic health

Elevated Hcy carries many short term (thrombosis) and long-term problems, best addressed ASAP

While short-term research (4-8 weeks) has been extensively studied and often shows good tolerability, long-term safety data is more limited, and several theoretical concerns warrant careful consideration

S-adenosyl methionine (SAMe), the active form of the amino acid methionine, is the major metabolite in multiple metabolic pathways on which neuronal homeostasis depends

Once the hepatic glutathione is depleted this toxic metabolite binds covalently to proteins and causes oxidative stress and cell necrosis