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Notably, outliers detected both at PRE-START and at the time of DARA treatment failure pointed to biologically distinct, potentially genetically driven MM subgroups with divergent therapeutic responses ( Figure 5 ) confirmed consistent detection of ADO and INO but revealed divergent dynamics, highlighting the need for personalized metabolic monitoring

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As vitamin B12 is not stored in the body, therefore excess amounts are often removed in urine

Journal of Pharmaceutical Sciences, 112(5), 2189-2204.

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