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Description

10.1038/sj.cdd.4401963 Cell Death Differ

* Pycnogenol

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKvarepsilon supports the anabolic demands of dendritic cell activation

264 It also regulates p62/SQSTM1 acetylation (K420/K435), which is critical for recognizing ubiquitinated protein aggregates, 265 and Hsp90 acetylation (K489), which enhances its interaction with LAMP-2A to promote CMA and reduce -synuclein aggregation in PD