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The patients selected for this study were matched by age, sex, and ethnicity

Arzneim Forsch Drug Res 42:211214 Moreno L, Martnez-Cuesta MA, Muedra V, Beltrn B, Esplugues J (1997) Role of the endothelium in the relaxation induced by propofol and thiopental in isolated arteries from man

[1] [4] The medication is administered as a once-weekly subcutaneous injection, with dosing typically initiated at 2.5 mg once weekly for 4 weeks, then increased by 2.5 mg every 4 weeks as needed and tolerated up to 15 mg