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Sulforaphane inhibits the acquisition of tobacco smoke-induced lung cancer stem cell-like properties via the IL-6/Np63/notch axis

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Thus, Rotenone used in the present study, inhibitor of complex I blocks the transfer of an electron from the iron-sulfur center N-2 to ubiquinone (Li et al ., 2003) increased superoxide(O 2 * - ) production from the FMN semiquinone radical during ethanol oxidation (Bailey et al ., 1999)

The homeostasis of cerebral iron is tightly regulated through a complex network of transport and storage proteins, involving transferrin (Tf), non-transferrin-bound iron (NTBI), transferrin receptor (TfR1), divalent metal transporter 1 (DMT1), ferroportin 1 (FPN1), ferroxidases such as hephaestin (HEPH) and ceruloplasmin (CP), and intracellular storage protein ferritin (Baringer et al., 2023)

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