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The molecular mechanisms underlying berberine-induced cell cycle arrest include the increase of cyclin-dependent kinase (CDKs) inhibitors, such as p21 and p27, and the decrease of Cyclin D1 [215]

Anti-heliobacter pylori and anti-inflammatory potential of salvia officinalis metabolites: in vitro and in silico studies

GSTs conjugate 4HNE to GSH, and the corresponding glutathionyl-4-HNE (GS-HNE) is actively transported out of cells via RLIP76, a multifunctional membrane transporter for GSH-conjugated compounds, and/or MRPs (multidrug-resistance proteins

Initially developed for managing type 2 diabetes, tirzepatide has been shown to significantly aid in weight loss by reducing appetite, increasing satiety, and improving glucose control