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With flaxseed oil , you get the omega-3 fatty acid Alpha Linolenic Acid in abundance

doi: 10.3389/fncel.2022.869779 159 MorlandC.LauritzenK

Pastor F, Kolonias D, Giangrande PH, Gilboa E

On the other hand, HIF-1 can also enhance RANKL expression via the JAK2/STAT3 signaling pathway, directly promoting RANKL-mediated osteoclast differentiation