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First, patients that undergo autologous stem cell transplant require collection of hematopoietic stem cells (CD34+) and the traditional method of collection is a bone marrow harvest done by a specialist but in patients with SCD this process yields CD34+ cells with suboptimal quantity and quality requiring multiple harvests, each harvesting procedure increasing the risk of triggering acute pain crisis

Its administration has been shown to decelerate disease progression in MRL/lpr lupus mouse models, demonstrating potential for broader clinical applications

Dietary oleic acid-induced CD36 promotes cervical cancer cell growth and metastasis via up-regulation Src/ERK pathway

Interestingly, GLP-1RAs appear to have pleiotropic effects extending to the lungs and airway highlighting interest in their immunometabolism contribution

doi: 10.3892/ijo.2017.3914 62 PolsterBMKinnallyKWFiskumG