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Manganese levels were known to be high but clinical toxicity was not documented until Fell and Reynolds described a neurological syndrome in children of irritability and Parkinsonian-like tremors which correlated with abnormal brain MRI findings.1 Both the symptoms and the MRI abnormalities slowly disappeared after manganese supplements were stopped

Further reading [edit] Flow cytometry in clinical diagnosis (4th ed.)

Long chain saturated and unsaturated fatty acids exert opposing effects on viability and function of GLP-1-producing cells: mechanisms of lipotoxicity

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N-acetylcysteine ameliorates chemotherapy-induced impaired anxiety and depression-like behaviors by regulating inflammation, oxidative and cholinergic status, and BDNF release