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Under physiological conditions, the antioxidant system in the body, covering antioxidant enzymes [superoxide dismutase, catalase (CAT), and glutathione (GSH) peroxidase (GPX)] and antioxidants (vitamins C and E, flavonoids, carotenoids, GSH, and micronutrients), is involved in maintaining the dynamic balance between ROS production and metabolism

[DOI] [PMC free article] [PubMed] [Google Scholar] 148.Egorov E., Ropo A., Group T.a.t.S

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The most favorable developmental outcomes are associated with early implementation of the ketogenic diet (89) and are most pronounced in individuals with relatively mild presentations of pyruvate dehydrogenase complex deficiency, such as childhood-onset ataxia (73)