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This same principle applies to all peptide-based medications

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Subsequently, Fe 3+ taken up into the cell is reduced to Fe 2+ by STEAP3 metalloreductase in the endosome and is then released into the labile iron pool of the cytoplasm by divalent metal transporter 1 (DMT1) [55]

that folate supplementation can also reduce the incidence of depression, especially in women (81)

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