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In rats, the extract also had a hypotensive effect, possibly by inhibiting SNS activity (424)

Leveraging the proximity effect enabled by this fibrillar framework, CRBN anchored on the network simultaneously mediates ubiquitination tagging of both AR and HSP90, thereby establishing a supramolecular platform for coordinated polyubiquitination and subsequent degradation of compartmentalized oncoproteins 30,33,46 (Fig

Cancer 138 , 149155 (2020)

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Body weight curves from 6 weeks old to 14 weeks old, C, D