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Given their complexity to perform and lack of supporting data, simpler and highly effective procedures such as the distal T-shunt have largely replaced proximal shunts in the modern era [18, 19]

Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase

Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the Copper-Chaperone-for-SOD

These studies, even in diabetic conditions (Seveljevic-Jaran et al., 2006

Its primary function is to disrupt the interaction between FOXO4 and the tumor suppressor protein p53, leading to the selective apoptosis of senescent cells and a deceleration of biological aging