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J Pineal Res 59(4):403419 Mannino G, Pernici C, Serio G, Gentile C, Bertea CM (2021) Melatonin and phytomelatonin: chemistry, biosynthesis, metabolism, distribution and bioactivity in plants and animalsan overview

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However, the level of ROS is regulated by exercise-induced adaptation in the cells which may prevent further ROS-induced damage (Scheele et al., 2009