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Compounding this, the lack of clear, harmonized regulatory frameworks for nano-herbal medicines slows their approval, as most products fail to meet uniform standards of safety, efficacy, and quality control

Analytical reproducibility relies on consistent retention behaviour, spectral conformity and molecular mass confirmation

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In practice: SARMs are less suppressive, dont convert to estrogen at the same rate, dont carry the same liver toxicity risk as oral steroids, and dont produce the same degree of androgenic side effects (hair loss, acne, prostate issues)