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This is often achieved through the activation of the transcription factor nuclear factor erythroid-2-related factor 2 (NRF2), which subsequently triggers the expression of various antioxidant enzymes, including superoxide dismutases (SODs), peroxiredoxins (Prxs), catalase (CAT), and glutathione peroxidases (GPxs)

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Integration of non-SMAD and SMAD signaling in TGF-beta1-induced plasminogen activator inhibitor type-1 gene expression in vascular smooth muscle cells

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Results: Among 29,628 stroke survivors (189 transgender and 29,439 cisgender), stroke prevalence was higher in transgender individuals (4.2% vs