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A recent review has documented this synergy (McGuire et al., Curr Rev Musculoskelet Med 2025)

Regular doses of Vitamin B12 are recommended to see the best results as our bodies do not store this vitamin for very long

Across both healthcare systems, female patients underwent approximately 2.3 times more tests than male patients

These supplements can be particularly helpful among people who are prone to low iron levels, especially if theyre unable to maintain a good iron status through diet alone, including ( pregnant people infants and young children people experiencing heavy periods frequent blood donors people with cancer people with gastrointestinal disorders, such as celiac disease, ulcerative colitis, or Crohns disease those who have undergone gastric surgery people with heart failure those taking iron-depleting medications, such as those used to reduce stomach acid people regularly partaking in heavy exercise those following a vegetarian or vegan diet people with blood disorders, such as thalassemia or sickle cell anemia people with alcoholism Its important to note that taking iron supplements when theyre unnecessary could harm your health, partially because they typically contain high doses of iron, which can cause digestive issues and reduce the absorption of other nutrients in your gut ( Taking these supplements unnecessarily may also cause cell damage, and in severe cases, result in organ failure, coma, or death