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Parkin-independent mitophagy controls chemotherapeutic response in cancer cells

This conclusion was further strengthened by using the JA receptor coi1 mutants that showed a lack of expression of R-sustained genes (Figure 4), thereby confirming the involvement JA signaling in R phase

In an in vivo experiment, five groups of different materials were injected into Bel7404 tumor-bearing mice, which were euthanized within 12 h to collect major organs