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Before the Category 2 restriction, GHK-Cu was a staple in compounded anti-aging and post-procedure formulationsused topically in serums and creams for photoaging, surgical wound recovery, and overall skin rejuvenation

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Most importantly, the procognitive/antidementia capacity of orally delivered dihexa was blocked by an intracerebroventricularly delivered HGF antagonist, as measured using the Morris water maze task of spatial learning