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For example, it was shown that changes in the microbial composition correlated with an increase in intestinal permeability in alcohol-dependent subjects (Leclercq et al., 2014)

Kim J, Kumar GS, Choi HW, Park D, Kim WJ

Vas J, Santos-Rey K, Navarro-Pablo R, Modesto M, Aguilar I, Campos M, Aguilar-Velasco JF, Romero M, Prraga P, Hervs V, Santamara O, Mrquez-Zurita C, Rivas-Ruiz F (2016) Acupuncture for fibromyalgia in primary care: a randomised controlled trial

For instance, a double-blind 12-month study showed administration of biotin (100 mg three times daily) reduced disability progression among individuals with progressive multiple sclerosis (64)