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In 2013, a clinical trial comparing phentermine as monotherapy or as part of a combined therapy, took place and resulted in a weight loss of 5.1% at 28 weeks follow-up period in favor of the combined phentermine/topiramate group.(see Table 10) Table 10

Originally developed for obesity and metabolic syndrome research , 5-Amino-1MQs ability to boost NAD levels, activate sirtuin pathways, and increase resting energy expenditure has made it a promising candidate in: Fat loss programs Enhancing calorie burn and mobilizing stored fat without muscle loss