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3.4 Evaluation of exacerbations A complete blood count and reticulocyte count should be done in individuals with SCD who have acute exacerbations and exhibit symptoms such as infections, fevers, aplastic crises, etc

The evolutionary advantage this provides is not fully understood but may in part relate to its neuroprotective properties discussed below, although it comes at a substantial cost associated with the incidence of, for example, gout and cardiovascular disease 1

Expert take: Fergie's trainer, Natasha Kufa, claims vinegar shots flush out fats in the colon, which helps the body digest food and curb cravings.

When side effects do occur, they are typically mild and may include: Mild gastrointestinal symptoms such as nausea, diarrhoea, or upset stomach, particularly when starting supplementation or taking high doses on an empty stomach Skin reactions including itching, rash, or a sensation of swelling, though these are uncommon Headache or dizziness in some individuals, particularly with intramuscular injections Injection site reactions (pain, redness, or swelling) when B12 is administered via intramuscular injection for deficiency treatment It is important to note that serious adverse effects are rare

On the left, an antegrade view looking down the esophagus into a hernia sac