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Fontana 2 and Jonathan Sexton 3 , (1)University of Michigan, (2)University of Michigan Medical Center, Ann Arbor, MI, (3)University of Michigan Medical Center Background: In efforts to develop more physiologic in vitro models of human drug-induced liver injury (DILI), directed differentiation of stem cells towards human liver cells and multicellular human liver organoids (HLOs) have been developed

Advances in antibody-mediated rejection In the last two decades, antibody-mediated rejection (ABMR) has become a major research focus in transplant medicine, and, today, our knowledge about molecular mechanisms and the manifold phenotypic presentation of this rejection type has improved substantially

Lu, Hormonal and cell density regulation of hepatic gamma-glutamylcysteine synthetase gene expression

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The standard chemotherapy agents used in CRC treatment include 5-FU, oxaliplatin, and irinotecan