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Our findings extend these observations by revealing that aberrant oxidative stress responses evidenced by mitochondrial superoxide production and lipid peroxidation strongly associate with caspase-1 activity, suggesting a crosstalk between oxidative stress and inflammasome activation in SARS-CoV-2 infection

To test whether the GSH rhythm is controlled by the clock mechanism, we measured GSH in heads of arrhythmic clock mutants with loss of cyc ( cyc 01 ) or per ( per 01 ) function

[DOI] [PMC free article] [PubMed] [Google Scholar] 107.Truban D., Hou X., Caulfield T.R., Fiesel F.C., Springer W

Mounting evidence suggests that cancer cells leverage mitochondrial function to regulate intracellular ROS, reprogram metabolic pathways, and modulate apoptosis and immune responses

doi: 10.1172/jci118522