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XieDJinJSunJLiangLWangXZhangWet al

Consequently, the findings are only preliminary and may not translate to the complex human disease

Biomolecules 5 , 545589 (2015)

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These pathway-level predictions were experimentally validated, as PYC significantly suppressed IL-6 and IL-1 expression in lipopolysaccharide-induced BV2 microglial cells, supporting its multi-component, multi-target mode of action ( Although in vitro studies have provided substantial evidence of anti-inflammatory activity, corresponding evaluations using in vivo models remain limited