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Some report that their migraine returns within 24 to 72 hours, which is part of why dexamethasone is sometimes included

Veterinary journal (London, England : 1997)

Acquired PGA elevation can also occur during chronic acetaminophen use [67, 68] as acetaminophen metabolism consumes glutathione through conjugation reactions, thereby depleting GSH stores and increasing metabolic flux toward PGA formation [69]