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In the vasculature, oxidative damage to DNA and proteins is implicated in extracellular matrix remodeling and arterial stiffening, a key contributor to cardiovascular aging [189]

Cancer Immunol Res 6:11001109 Zhang M et al (2024) Optimizing CAR-T cell culture: differential effects of IL-2, IL-12, and IL-21 on CAR-T cells

Moreover, in the metabolism of prostaglandins, leukotrienes, steroids, and melanin byproducts of GSH are formed after conjugation with the endogenous metabolites