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Namely, the authors indicated that protein carbonylation could likely alter protein-water molecular interactions by (i) modification of the isoelectric point in oxidized proteins and (ii) by formation of protein aggregates

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Cycle lytes, VPA, and ammonia levels q2-4 initially (NH3 doesnt always track with valproic acid level)

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However, this issue requires more clinical studies to determine the appropriate dose and confirm its effectiveness in treating this disease