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Long COVID or post-acute Sequelae of COVID-19 (PASC): an overview of biological factors that may contribute to persistent symptoms

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doi:10.1038/tp.2012.61, PMID: 22781167 Mathew SJ, Murrough JW, Mao X, Pillemer S, Shungu DC (2010) Proton magnetic resonance spectroscopy measurement of brain glutathione supports increased oxidative stress in major depressive Ddsorder

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10.1016/j.nbd.2021.105455 20 LvY.-b.ZhouQ.YanJ.-x.LuoL.-s.ZhangJ.-l

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Current clinical diagnostic tools are often inadequate for identifying the underlying mechanisms driving these symptoms, and this is a reflection of the broader challenge of understanding the complex and multifactorial nature of these disorders (Rosenthal et al., 2008)

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Although this mechanism requires further validation, it is consistent with existing evidence that BACH1 promotes angiogenesis under antioxidant conditions. In conclusion, this study systematically elucidated the intracellular molecular mechanism of BPC157 through multimethod validation, addressing a critical knowledge gap in its pharmacological profile

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