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Projects may involve metabolite-like glutathione adducts, labeled GSH derivatives, linker-bearing intermediates, or repeatable builds needed for DMPK, toxicology, chemical biology, or assay development

(2020) The antiaging activity of ergothioneine in UVA-irradiated human dermal fibroblasts via the inhibition of the AP-1 pathway and the activation of Nrf2-mediated antioxidant genes

Immune cells, such as macrophages, are recruited to the site of tumor growth, and their activity further increases ROS production, contributing to a positive feedback loop that sustains inflammation and supports melanoma cell survival 71

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