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Given the up-regulation of several genes involved in mitochondrial transcription and translation, we investigated Mitochondrial Transcription Factor A ( TFAM ), a nuclear-encoded transcription factor essential for mtDNA transcription and replication [37], as a potential master regulator driving this program

t = 0.352

Higher levels of serum vitamin D were shown to reduce diabetes risk in a diverse population (Chatterjee 2023)

The diagnosis of MS is made according to clinical, radiological and, recently, biochemical criteria 3 and after diagnosis, early prediction of MS outcomes is a challenge because, until now, there is no strong candidate biomarker able to detect, early during disease course, those people with MS (pwMS) with subclinical neuronal damage and, therefore, more prone to develop clinical progression and functional impairment over time 4