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(2003) 19:S8799

The HPV protein's dependence on DNA damage responses in infected cells to facilitate the replication of its genome may represent a joining between smoking-induced DNA damage and HPV pathogenesis [149]

Consequently, this metabolic pathway is the main source of superoxide and hydrogen peroxide, which, at the same time, lead to propagation of free radicals contributing to the disease

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The intensity of MitoTracker fluorescence was decreased in Fabry kidney organoids but recovered after ERT, although it remained weaker than that in WT kidney organoids (Fig