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Preclinical studies in murine and human alveolar macrophages (AMs) have demonstrated that loperamide induced autophagy, enhancing its antimicrobial activity towards M.tb [12]

Despite the evolutionary pressure to avoid the high expression of proteins with large hydrophobic surfaces, the brain paradoxically expresses such proteins at elevated levels 40

Studies in the field of accelerated aging have established a link between PARP activation and impaired mitochondrial health, which is associated with reduced NAD + levels resulting from PARP hyperactivation 158

The experimental group underwent conventional therapy for a minimum of three months after receiving subcutaneous injections of V

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