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This must be due to a lower clearance (CL) of drug B, since it was shown above that the volume of distribution is similar for both drugs

These effects could also be partly regulated by increased levels of endocannabinoids or through TRP channels, since CBD has a relatively high affinity for TRP vanilloid receptor 1 (TRPV1), which has been shown to modulate cytokine production in microglia (Stampanoni Bassi et al., 2019)

Appl Microbiol Biotechnol 104, 24112425 (2020) 3

Se recomienda administrar una suplementacin de Glutatin cuando el desequilibrio REDOX est presente en el organismo como por ejemplo: En el proceso de envejecimiento prematuro, en enfermedades inmunitarias (ya sea deficiencia o autoinmunes), pacientes con dao heptico, casos de post-infarto cardiaco, diabetes mellitus, enfermedades neurodegenerativas (como por ejemplo el Alzheimer, Parkinson, demencia senil, etc.), toxicidad por mercurio o cadmio, personas deportistas, post-traumticos, post-quirrgicos, entre otros