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The expression of nutrient transporters, such as GLUT1 and LAT1, has been shown to be high in both, the BBB and in glioma (207, 208), which led to the development of different transporter-utilizing anti-cancer drug delivery strategies in order to reach the cancer cells residing beyond the intact BBB (Table II)

[115] Dehalogenases In humans, two major coenzyme B 12 -dependent enzyme families corresponding to the first two reaction types, are known

Cryopreservation involves the surgical removal of ovarian tissue via laparoscopy or laparotomy, excluding the medulla while retaining the cortex, which is then sectioned into slices approximately 1 mm thick and 510 mm in length and width

December 5 Product: AstraZenecas Imfinzi Indication: Limited-stage small cell lung cancer AstraZeneca on Wednesday successfully expanded the label of its PD-L1 blocker Imfinzi (durvalumab), notching the FDAs greenlight for its use in patients with limited-stage small cell lung cancer who have not progressed after concurrent platinum chemotherapy and radiation therapy