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Because a risk factor for severe konzo disease could cluster in families, we asked whether GPx3 levels might vary between families with different stages of konzo disease, even for unaffected siblings

Therefore, we performed our mitochondrial analyses upon 20 h of starvation to ensure sufficient nutrient stress in the absence of a loss of cell viability

738 Abnormal xCT function causes GSH depletion and sufficiently triggers ferroptosis

Reimagining Rural India: CEAHs Vision for Animal Husbandry in Viksit Bharat In an exclusive interaction, Dr Mahesh PS, Joint Commissioner and Director of CEAH, shares insights on the future of India's livestock sector

GPX4 specifically catalyzes the oxidative activity of lipid peroxides in a glutathione-dependent manner, thus protecting cells from the threat of ferroptosis [12, 17, 18]