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Haithcock D, Jiao H, Cui XL, Hopfer U, Douglas JG

Kjaerstad HL, Sohol K, Vinberg M, Kessing LV, Miskowiak KW (2023) The trajectory of emotional and non-emotional cognitive function in newly diagnosed patients with bipolar disorder and their unaffected relatives: a 16-month follow-up study

At standard doses, naltrexone functions as an opioid receptor antagonist used for addiction treatment, but at significantly lower doses (typically 1.5-4.5mg), it exerts unique effects on immune regulation and inflammatory pathways that appear beneficial for autoimmune conditions

A clinician may consider: Complete blood count (CBC) Ferritin and iron studies, including transferrin saturation Vitamin B12, with additional testing when symptoms and the B12 result do not align Folate Vitamin D Calcium and parathyroid hormone Albumin and other markers relevant to protein and overall nutrition Electrolytes, kidney and liver markers Thiamine, copper, zinc or vitamins A, E and K when the procedure or symptoms indicate The individual numbers are only part of the assessment

doi: 10.1038/s41584-018-0058-9 30 DonatoRCannonBRSorciGRiuzziFHsuKWeberDJet al