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Famularo G, Matricardi F, Nucera E, Santini G, De Simone C: Carnitine deficiency: Primary and secondary syndromes

Anti-EphA2 antibodies (B233, B208, and EA5) and a secondary saporin (toxin) labeled monoclonal antibody (mAb) which recognizes the anti-EphA2 antibodies were coincubated and introduced to a tumor cell based monolayer (MCF-10A) and incubated for 72-96 hours

the authors attributed this result to the lipid extraction pretreatment boosting the ORR active center by increasing its pyridinic N (27.8%) and graphitic N (40.3%) contents

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Additionally, research has identified several metal homeostasis regulators, such as MTF1 and ZnT1, that participate in WD-related copper toxicity by interacting with copper ions or competitively binding to shared sites, thereby influencing intracellular copper concentrations (53,143)