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ARQ761 is under clinical evaluation with Gemcitabine and Nab-paclitaxel (NCT02514031) for treating NQO1-overexpressing tumors

Therefore, the effects of MOX and MOX-Cu on the generation of intracellular ROS and the accumulation of lipofuscin were analyzed with the aim to reveal the oxidative stress in C

GABA can also be taken up by presynaptic neurons after its release into the synapsis

CAM increased cellular Ca 2+ uptake by regulating L-type voltage-dependent Ca 2+ channels, resulting in elevated ROS production and increased Fe 2+ levels, ultimately inducing ferroptosis in lung cancer cells

Myeloid cells act as detectors of viral infections and are a key component of the antiviral response, including the coordination of immune responses and tissue homeostasis repair mechanisms